聯(lián)系我們/CONTACT US

聯(lián)系人：錢經(jīng)理

電話：13636351217

手機：13636351217，13636351073

地址：上海市松江臨港科技城漢橋文化科技園B座

郵編：201615

傳真：021-64881400

郵箱：2881726255@qq.com

阿儀網(wǎng)商鋪：http://www.app17.com/c60514/

手機網(wǎng)站：m.shhyswkj.com

產(chǎn)品分類/PRODUCT CLASS

產(chǎn)品簡介

Rabbit Anti-TLR4

價格：電議

采購度：812 原產(chǎn)地：其它

發(fā)布時間：2018/6/25 11:04:13

Rabbit Anti-TLR4 Six human homologs of the Drosophila Toll receptor were initially identified based on their sequence similarities and designated toll-like receptors (TLR).

分享到：

標簽：Rabbit Anti-TLR4

詳細信息

Rabbit Anti-TLR4
Background: Six human homologs of the Drosophila Toll receptor were initially identified based on their sequence similarities ａnd designated toll-like receptors (TLR).
Toll receptors are involved in mediating dorsoventral polarization in the developing Drosophila embryo ａnd also participate in the host immunity. The TLR family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLR1, as well as the other TLR family members, are type I transmembrane receptors that characteristically contain an extracellular domain consisting of several leucine-rich regions along with a single cytoplasmic Toll/IL-1R-like domain. TLR2 ａnd TLR4 are activated in response to lipopolysacchride (LPS) stimulation, which results in the activation ａnd translocation of NFκB ａnd suggests that these receptors are involved in mediating inflammatory responses. Expression of TLR receptors is highest in peripheral blood leukocytes, macrophages ａnd monocytes. TLR6 is highly homologous to TLR1, sharing greater
than 65% sequence identity; like other members of TLR family, it induces NFκB signaling upon activation.

specificity :
–Anti- TLR4 is a rabbit polyclonal antibody raised against amino acids 339-638 mapping within an N-terminal extracellular domain of TLR4
–specific for TLR4 of human, mouse ａnd rat,pig,cow,chicken
–use for western blotting,elisa,immunoprecipitation ａnd immunohistochemistry
–Protein G affinity chromatography purification, purity :>95%
–Isotype: IgG
–mol wt: 95 kDa

Application :
–Western blotting 1:100-500
–Immunohistochemistry 1:100-500
–ELISA 1:500-1000
–Optimal working dilutions must be determined by the end user.
Storage: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month ａnd for greater than a year when kept at -20℃. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody, the antibody is stable for at least six weeks at 2-4 ℃
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

更新時間：2024/11/18 9:49:20

在線留言

在線咨詢，尊敬的客戶您好，我們會盡快回復您的咨詢！

您感興趣的產(chǎn)品*		您還沒有輸入您感興趣的產(chǎn)品
您的單位*		您還沒有輸入您的單位
聯(lián)系人*		您還沒有輸入聯(lián)系人
聯(lián)系電話*		您還沒有輸入聯(lián)系電話
詳細地址
常用郵箱		您輸入的郵箱格式不正確
請輸入您對我們的意見或建議*		您還沒有輸入您對我們的意見或建議
驗證碼*		您還沒有輸入驗證碼